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By Erika Powers VIRTUAL -- June 8, 2021 -- Patients with early rheumatoid arthritis (RA) who received treatment with tocilizumab had gene expression differences at baseline, in both whole blood and peripheral blood mononuclear cells (PBMC) RNA samples, that predicted response to tocilizumab,...
The US Food and Drug Administration (FDA) has granted accelerated approval to aducanumab (Aduhelm) for the treatment of Alzheimer’s disease -- the first novel therapy approved for Alzheimer’s disease since 2003. Accelerated approval can be based on the drug’s effect on a surrogate endpoint that is...
The US Food and Drug Administration (FDA) approved brincidofovir (Tembexa) to treat smallpox. Although the World Health Organization declared smallpox, there have been long standing concerns that the virus that causes smallpox, the variola virus, could be used as a bioweapon. Before its...
For older individuals with type 1 diabetes, severe hypoglycaemic and hyperglycaemic events are associated with increased future risk of dementia, according to a study published in the journal Neurology. Older people with type 1 diabetes who had been to the hospital at some point for both...
By Eric Ramos VIRTUAL -- May 26, 2021 -- A systematic review and meta-analysis that included over 1 million proton pump inhibitor (PPI) users, presented at Digestive Disease Week (DDW) 2021, found no association between PPI use and colorectal cancer risk. “Long-term PPI use has raised concerns...
By Shazia Qureshi VIRTUAL -- May 25, 2021 -- In patients with newly diagnosed type 2 diabetes, using a combination treatment of vildagliptin plus metformin reduced the risk of initial treatment failure by 41% versus initiating treatment with metformin alone, according to a study presented at the...
By Shazia Qureshi VIRTUAL -- May 25, 2021 -- Calcifediol appears to be superior to cholecalciferol in increasing levels of 25-hydroxyvitamin D (25[OH]D) over 1 year of treatment in postmenopausal women with vitamin D deficiency, according to a study presented at the Virtual 23rd European Congress...
Intralymphatic administration of aluminum-formulated glutamic acid decarboxylase (GAD-alum), combined with vitamin D supplementation, seems to preserve C-peptide in patients with recent-onset type 1 diabetes carrying HLA DR3-DQ2, according to a study published in Diabetes Care. The phase 2 double-...
By Nancy Melville VIRTUAL -- May 24, 2021 -- The use of prophylactic ursodeoxycholic acid (UDCA) in patients undergoing bariatric surgery is associated with a significant reduction in the risk of the development of gallstones, but only among patients with no evidence of gallstones at prior to...
By Walter Alexander VIRTUAL -- May 20, 2021 -- Compared with a sham procedure, ultrasound-based renal denervation safely reduced blood pressure (BP) in patients with hypertension resistant to a standardised single tablet combination of 3 guideline-recommended medications, according to a study...

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